TruTrim: Medical Weight Loss with FDA-Approved GLP-1 Medications in Newburyport, MA
Struggling to lose weight and keep it off, even with diet and exercise?
What is GLP-1 weight loss at TruWellness?
It is medically supervised weight loss with an FDA-approved GLP-1 medication as part of our TruTrim program. TruWellness prescribes all FDA-approved GLP-1 medications, such as semaglutide and tirzepatide. Medication is paired with personalized nutrition plans, regular monitoring and ongoing support from our experienced team.
- Pricing tailored to your individual needs
- All FDA-approved GLP-1 medications
- Medically supervised
- Regular monitoring
Medically reviewed by Dr. Mark Su, MD, FAAFP, Medical Director · Updated October 2026
How do GLP-1 medications like semaglutide and tirzepatide work?
Semaglutide is a medication that helps control appetite and regulate blood sugar levels, making weight loss more manageable. Tirzepatide acts on two appetite and blood-sugar hormone pathways, GIP and GLP-1. Both are taken as a once-weekly injection.[1][2]
Semaglutide
A GLP-1 receptor agonist taken once a week. In the STEP 1 trial, adults taking weekly semaglutide lost an average of 14.9% of their body weight over 68 weeks, compared with 2.4% on placebo.[1]
Tirzepatide
A once-weekly medication that acts on both GIP and GLP-1 receptors. In the SURMOUNT-1 trial, adults lost an average of 15.0% to 20.9% of their body weight over 72 weeks, depending on dose, compared with 3.1% on placebo.[2]
Individual results vary. In these trials, medication was combined with a reduced-calorie diet and increased physical activity.
Who is a candidate for GLP-1 weight loss?
Prescription GLP-1 weight-loss medications are approved for adults with a body mass index (BMI) of 30 or higher, or 27 or higher with at least one weight-related health condition, such as high blood pressure, type 2 diabetes or high cholesterol.[3][4]
Your TruTrim program begins with an in-depth assessment of your metabolic profile to identify the most effective treatment options for you. Your provider reviews your health history and decides whether a GLP-1 medication is right for you.
What side effects should I expect, and how am I monitored?
The most common side effects are digestive, such as nausea, diarrhea, vomiting and constipation.[3][4] In the major trials, these were mostly mild to moderate and tended to ease over time.[1][2]
We believe that successful weight loss goes beyond medication. That’s why our TruTrim program includes regular monitoring and personalized support to ensure sustainable and healthy weight management, with an approach that encompasses physical and mental health aspects.
- Personalized Plans: customized strategies based on your unique health profile and goals.
- Nutritional Support: guidance on effective dietary choices to fuel your body and promote fat loss.
- Supplement Recommendations: expert advice on supplements that can enhance metabolism and support overall well-being.
- Expert Guidance: ongoing support from our experienced team to help you stay on track.
What else can support my weight loss?
Our TruTrim program may also include HCG and B12 MIC (Skinny Shot) injections, and you can measure your metabolism with RMR testing.
Vitamin & wellness injections
B12 MIC Skinny Shots: a blend of Vitamin B12, Methionine, Inositol and Choline that boosts metabolism and energy.
VO2 max & RMR testing
Measure your real resting metabolic rate and body composition to guide your nutrition plan.
CoolSculpting®
Close to your goal? CoolSculpting® targets stubborn fat pockets without surgery or downtime.
Tracking muscle while you lose weight? Our Seca® body composition scan takes about 5 minutes and shows changes in fat mass and muscle mass, beyond the number on the scale.
From The Su TruReport
Straight answers from Dr. Mark Su, MD, FAAFP, from his podcast, on topics related to this treatment.
GLP-1 Weight Loss in Newburyport: Semaglutide & Tirzepatide
Dr. Mark Su answers the questions people actually ask about GLP-1 medications in plain English, including the difference between semaglutide and tirzepatide.
Read article →
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Asked for the single best thing to take for longevity, Dr. Mark Su gives a four-part answer: creatine, NAD, HRT and biological age testing. He also explains why VO2 max matters.
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The Brain Health Playbook: Movement, Red Light, Hyperbaric Oxygen and Nutrition
Dr. Mark Su and Dr. Trevor Berry, a board-certified chiropractic neurologist, share four pillars of brain health: movement, red light and low-level laser, oxygen therapies like hyperbaric, and nutrition. Their message: don’t wait for symptoms to start.
Read article →Meet your providers
Dr. Mark Su, MD, FAAFP
Medical Director
Board-certified in Family Medicine and in practice since 2003. His specialty of interest focuses on causes of chronic inflammation.
Mary Ramsey Stuckey, PA‑C
Physician Assistant (PA‑C)
Her focus has grown into functional medicine, with particular interest in nutrition, gut health and hormones.
GLP-1 weight loss: common questions
Do you offer semaglutide and tirzepatide?
Yes. TruWellness prescribes all FDA-approved GLP-1 medications, including semaglutide and tirzepatide, as part of TruTrim when they are right for you. Your provider decides after an in-depth assessment of your metabolic profile and health history.
Is GLP-1 treatment medically supervised?
Yes. GLP-1 treatment is part of TruTrim, our personalized, medically supervised program, which includes regular monitoring, nutrition plans and ongoing support.
Take the first step toward a healthier you
Contact us today to schedule a consultation. Ask us about our monthly memberships to enjoy ongoing support, exclusive benefits and continuous optimization of your health and wellness journey.
TruWellness · 255 Low Street, Suite 303, Newburyport, MA 01950 · Monday to Friday, 9:00 am to 5:00 pm
References
- Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989-1002. PMID: 33567185. doi:10.1056/NEJMoa2032183 pubmed.ncbi.nlm.nih.gov/33567185/
- Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205-216. PMID: 35658024. doi:10.1056/NEJMoa2206038 pubmed.ncbi.nlm.nih.gov/35658024/
- U.S. Food and Drug Administration-approved prescribing information: WEGOVY® (semaglutide) injection. Novo Nordisk. DailyMed, U.S. National Library of Medicine. dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b
- U.S. Food and Drug Administration-approved prescribing information: ZEPBOUND® (tirzepatide) injection. Eli Lilly and Company. DailyMed, U.S. National Library of Medicine. dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
This page is for general education and is not medical advice. Individual results vary. A TruWellness provider will review your health history before any treatment. Medically reviewed by Dr. Mark Su, MD, FAAFP, Medical Director.
